Télécharger le livre :  Substance Use Disorders
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The purpose of this book is to provide a broad scope of substance use disorder research and how these findings can impact treatment outcomes.The research and outcomes described in this book represent important principles related to identifying and understanding factors...

Editeur : Springer
Parution : 2020-05-19
Collection : Handbook of Experimental Pharmacology
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147,69
Télécharger le livre :  Lipid Signaling in Human Diseases
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Lipids are an integral part of cell membrane architecture, are intermediaries in cell metabolism, and are involved in transmitting cell signals from hormones, growth factors and nutrients. A number of lipases and phospholipases, lipid kinases, lipid phosphatases,...

Editeur : Springer
Parution : 2020-04-24
Collection : Handbook of Experimental Pharmacology
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147,69
Télécharger le livre :  Good Research Practice in Non-Clinical Pharmacology and Biomedicine
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This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and...

Editeur : Springer
Parution : 2020-02-20
Collection : Handbook of Experimental Pharmacology
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Télécharger le livre :  Concepts and Principles of Pharmacology
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Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape...

Editeur : Springer
Parution : 2019-12-24
Collection : Handbook of Experimental Pharmacology
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168,79
Télécharger le livre :  Bile Acids and Their Receptors
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This book focusses on the latest results related to the field of  bile acids as signaling molecules  and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this...

Editeur : Springer
Parution : 2019-09-03
Collection : Handbook of Experimental Pharmacology
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105,49
Télécharger le livre :  Sleep-Wake Neurobiology and Pharmacology
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This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease,...

Editeur : Springer
Parution : 2019-09-03
Collection : Handbook of Experimental Pharmacology
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147,69
Télécharger le livre :  Calcitonin Gene-Related Peptide (CGRP) Mechanisms
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This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease.This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing...

Editeur : Springer
Parution : 2019-08-31
Collection : Handbook of Experimental Pharmacology
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94,94
Télécharger le livre :  The Nociceptin/Orphanin FQ Peptide Receptor
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The aim of this book is not only to introduce readers with a broad spectrum of biological actions of the NOP receptor, but also to feature a detailed look at the N/OFQ-NOP receptor system, medicinal chemistry, pharmacology, and clinical data of NOP-targeted ligands....

Editeur : Springer
Parution : 2019-07-13
Collection : Handbook of Experimental Pharmacology
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147,69
Télécharger le livre :  Antidepressants
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This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs.

Editeur : Springer
Parution : 2019-05-31
Collection : Handbook of Experimental Pharmacology
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147,69
Télécharger le livre :  Brown Adipose Tissue
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The main focus of this book is on brown adipose tissue and its metabolic function.The book provides a timely update on the latest research and shows where the field is heading. Brown adipose tissue (BAT) dissipates energy and has received considerable attention in the...

Editeur : Springer
Parution : 2019-04-02
Collection : Handbook of Experimental Pharmacology
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210,99
Télécharger le livre :  The Neuropharmacology of Alcohol
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This volume gives an overview of new insights to alcohol pharmacology using DREADDs (Designer Receptors and Unraveling the Neuropharmacology of Alcohol). It examines which pharmacological principles should be applied to understanding DREADDs taking into account some...

Editeur : Springer
Parution : 2019-03-27
Collection : Handbook of Experimental Pharmacology
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220,49
Télécharger le livre :  New Psychoactive Substances
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This volume is designed to feature the pharmacology of new psychoactive substances, legislative aspects, information exchange including epidemiology, and clinical, forensic, and analytical toxicology in order to facilitate the understanding of this complex and rapidly...

Editeur : Springer
Parution : 2019-02-20
Collection : Handbook of Experimental Pharmacology
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158,24
Télécharger le livre :  Mechanisms of Drug Resistance in Cancer Therapy
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A major objective of this book is to reveal unprecedented opportunities to understand and overcome drug resistance through the clinical assessment of rational therapeutic drug combinations and the use of predictive and prognostic biomarkers to enable patient...

Editeur : Springer
Parution : 2019-01-10
Collection : Handbook of Experimental Pharmacology
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147,69
Télécharger le livre :  Delta Opioid Receptor Pharmacology and Therapeutic Applications
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This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system...

Editeur : Springer
Parution : 2018-09-27
Collection : Handbook of Experimental Pharmacology
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116,04
Télécharger le livre :  Voltage-gated Sodium Channels: Structure, Function and Channelopathies
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This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their structure-function, their pharmacology and related diseases. Among the topics discussed are the structural basis of Na+ channel function, methodological advances in the study...

Editeur : Springer
Parution : 2018-06-04
Collection : Handbook of Experimental Pharmacology
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147,69
Télécharger le livre :  Targeting Trafficking in Drug Development
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Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as well as a clear understanding of the individual components of cellular...

Editeur : Springer
Parution : 2018-04-18
Collection : Handbook of Experimental Pharmacology
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220,49
Télécharger le livre :  Sigma Proteins: Evolution of the Concept of Sigma Receptors
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Two sigma receptor subtypes have been proposed, sigma1 and 2. Much of our understanding of this system is based on biochemical and pharmacological characterization of the cloned sigma1 receptor subtype (Sigma1). It has become clear that sigma receptors are not canonical...

Editeur : Springer
Parution : 2017-10-05
Collection : Handbook of Experimental Pharmacology
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336,54
Télécharger le livre :  Pharmacology of Mitochondria
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This special book is conceived to highlight mitochondrial structural and functional integrity and how they are associated with several human diseases such as cardiovascular, cancer, renal, neurological disorder, and genetic disorders. The chapters contributed by...

Editeur : Springer
Parution : 2017-08-11
Collection : Handbook of Experimental Pharmacology
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283,79
Télécharger le livre :  Heart Failure
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This special issue of the Handbook of Experimental Pharmacology on Heart Failure covers the entire spectrum of the field, from the current understanding and definitions of heart failure, to epidemiology and the importance of co-morbidities, clinical trial design and...

Editeur : Springer
Parution : 2017-06-09
Collection : Handbook of Experimental Pharmacology
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241,59
Télécharger le livre :  Pharmacologic Therapy of Ocular Disease
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There have been major advancements in the pharmacologic treatment of eye diseases over the past decade. With newly discovered disease targets and novel approaches to deliver therapeutic compounds to the eye, patients are seeing improved outcomes. Not only are there...

Editeur : Springer
Parution : 2017-06-05
Collection : Handbook of Experimental Pharmacology
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304,89
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