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The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.
Editeur :
Humana
Parution :
2011-09-18
Collection :
Cancer Drug Discovery and Development
ePub
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This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate...
Editeur :
Wiley
Parution :
2011-09-09
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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We are celebrating this year the hundred years´ anniversary of allergen-specific immunotherapy. In 1911 Leonard Noon published his seminal work “Prophylactic inoculation against hay fever” describing his attempts to achieve active immunity against “grass pollen toxin”...
Editeur :
Springer
Parution :
2011-08-26
Collection :
Current Topics in Microbiology and Immunology
ePub
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Pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problems. This introductory guide is designed to aid the rapid understanding of the key principles of...
Editeur :
Wiley-Blackwell
Parution :
2011-08-24
ePub
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The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease.The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper...
Editeur :
Springer
Parution :
2011-08-23
ePub
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This book reviews the epidemiological associations between insulin resistance and cancer. This is followed by reviews of animal models which support this relationship and provide insight into potential mechanisms. Several chapters then provide detailed examination of...
Editeur :
Springer
Parution :
2011-08-19
Collection :
Energy Balance and Cancer
PDF, ePub
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Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic...
Editeur :
Wiley
Parution :
2011-08-10
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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Breast cancer is a complex disease caused by multiple environmental and lifestyle factors interacting with genetic susceptibility across the life span. Therefore, environmental factors are of intense interest to both researchers and community members, including women...
Editeur :
Springer
Parution :
2011-08-10
ePub
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The book addresses the basics, applications, and manufacturing of plasmid biopharmaceuticals.The survey of the most relevant characteristics of plasmids provides the basics for designing plasmid products (applications) and processes (manufacturing). Key features that...
Editeur :
Wiley
Parution :
2011-08-04
PDF, ePub
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This book overviews and integrates the business and technical issues that pharmaceutical companies need to know in order to combat the major global problem of counterfeit medicines. In addition to discussion of the problems, the author Davison addresses analytical...
Editeur :
Wiley
Parution :
2011-08-04
PDF, ePub
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Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agentsDrug discrimination can be described as a "drug detection" procedure that uses a pharmacologically active agent as...
Editeur :
Wiley
Parution :
2011-08-04
PDF, ePub
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Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and...
Editeur :
Wiley
Parution :
2011-08-04
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular...
Editeur :
Wiley-VCH
Parution :
2011-08-04
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Discover new and emerging applications for microdialysis in drug evaluation Microdialysis is a highly valuable sampling tool that can be used in vivo to measure free, unbound analyte concentrations located in interstitial and extracellular spaces. This book explores the...
Editeur :
Wiley
Parution :
2011-07-13
PDF, ePub
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The definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range of illnesses; however, their efficacy can be severely impaired by their immunogenicity. When introduced into the body,...
Editeur :
Wiley
Parution :
2011-07-12
PDF, ePub
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This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by...
Editeur :
Wiley
Parution :
2011-07-08
ePub
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This is a second edition to the original published by Springer in 2006. The comprehensive volume takes a textbook approach systematically developing the field by starting from linear models and then moving up to generalized linear and non-linear mixed effects models....
Editeur :
Springer
Parution :
2011-07-01
ePub
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Are you about to sit your pharmacology exams? Do you lack confidence in prescribing? Would it help to have a quick reference, pocket-sized reassurance on common drugs and the conditions that they are used in? The Hands-on Guide to Clinical Pharmacology is the perfect...
Editeur :
Wiley-Blackwell
Parution :
2011-06-15
Collection :
Hands-on Guides
PDF, ePub
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The majority of cancers present at a relatively advanced stage in which invasion within the primary organ is well established and metastases to lymph and distant organs are either clinically apparent or present at the microscopic level. However, it is increasingly...
Editeur :
Springer
Parution :
2011-05-07
ePub
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Folate pathways are essential in metabolism and macromolecule synthesis. Antifolate drugs that are largely transported via a high capacity folate transporter (i.e. the reduced-folate carrier) and inhibit folate-dependent enzymes include the dihydrofolate reductase...
Editeur :
Springer
Parution :
2011-05-05
ePub
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